# Matthew J. Ryan Veterinary Hospital of the University of Pennsylvania Canonical URL: https://heypaww.com/vets/clinic/matthew-j-ryan-veterinary-hospital-of-the-university-of-pennsylvania-philadelphia-pa-20718 Veterinary clinic listing in Philadelphia, PA. - Address: 3900 Spruce Street, Philadelphia, PA, 19104 - Phone: (215) 898-8884 [Directions in Google Maps](https://www.google.com/maps/dir/?api=1&destination=3900%20Spruce%20Street%2C%20Philadelphia%2C%20PA%2C%2019104) Directory snapshot: September 16, 2026. Contact the clinic directly to confirm its address, availability, hours, and services. Map coordinates are approximate; this is not a verified entrance. Paww is an independent directory and does not provide veterinary care or endorse this listing.